Adjunctive Use Of Hyaluronic Acid With Scaling & Root Planing In Treatment of Chronic Periodontitis Patients With Diabetes Mellitus Type 2: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Gain in clinical attachment level
研究概览
简要总结
The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling & root planing (SRP) in patients with chronic periodontitis & diabetes mellitus type 2.
详细描述
Thirty subjects with chronic periodontitis & diabetes mellitus type 2 were included in this randomized clinical trial. These subjects were randomly allocated into test & control equal groups. The test group comprised fifteen patients who received SRP with subgingival application of Hyaluronic acid as an adjunct. The control group included fifteen patients who received SRP alone. Plaque index (PI), gingival index (GI), probing depth (PD) & clinical attachment level (CAL) were measured & documented at baseline, 6 weeks & 12 weeks intervals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 38 Months 至 56 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with chronic periodontitis and type 2 diabetes mellitus
- •Minimum of 20 teeth
- •Clinical attachment level (CAL) ≥ 3 mm
- •Probing depth (PD) ≥ 4 mm.
排除标准
- •Pregnant females
研究组 & 干预措施
SRP group
Chronic periodontitis patients with type 2 diabetes mellitus recieved Periodontal treatment in the form of scaling & root planing (SRP) alone.
干预措施: Scaling & root planning alone (Procedure)
Hyaluronic acid & SRP group
Chronic periodontitis & type 2 diabetes mellitus patients received Periodontal treatment in the form of scaling & root planing (SRP) with the adjunctive use of hyaluronic acid.
干预措施: Periodontal treatment with Hyaluronic acid associated with SRP (Procedure)
结局指标
主要结局
Gain in clinical attachment level
时间窗: 12 weeks
Gain in clinical attachment level will be measured in millimeter by William's graduated periodontal probe
次要结局
未报告次要终点
研究者
Gihane Gharib Madkour
Associate Professor
Cairo University