The effect of bromelain in inflammatory bowel disease

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 84

Inclusion Criteria

Diagnosis of inflammatory bowel disease based on the diagnosis of a gastroenterologist
Having mild to moderate disease activity in ulcerative colitis and mild to moderate disease activity in Crohn's
Minimum age of 18 years and maximum of 70 years
People express their satisfaction to participate in the study

Exclusion Criteria

Smoking
Alcohol consumption in the last 1 month
Pregnancy and breastfeeding
The consumption of antioxidant, vitamin and mineral supplements in the last 2 months
The consumption of antidepressants
The consumption of anticoagulant drugs
The consumption of drugs against tumor necrosis factor alpha
The consumption of steroidal and non-steroidal anti-inflammatory agents, antibiotics, fiber, probiotic during the two weeks before the intervention.
Having kidney diseases
Having liver diseases
Having thyroid diseases
Having diabetes
Having hypotension and hypertension
Having cardiovascular disease
Having Biliary diseases
Having endocrine diseases
Having mental disorders or neurological diseases
Having Cushing's syndrome
Having polycystic ovary syndrome
Having anemia
Having hemophilia
Having leukopenia
Having thrombocytopenia
Having asthma
Having cancer
Having anorexia and bulimia nervosa
Having autoimmune diseases
Having gastroesophageal reflux disease
Other gastrointestinal diseases and extensive gastrointestinal surgeries that affect the condition of the disease
Having other chronic inflammatory and autoimmune diseases according to the physician diagnosis

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
lcerative colitis disease activity questionnaire score. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Ulcerative Colitis disease Activity Evaluation Questionnaire.;Crohn disease activity questionnaire score. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Crohn disease Activity Evaluation Questionnaire.

Secondary Outcome Measures

Name	Time	Method
Quality of life questionnaire score in inflammatory bowel disease. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Quality of life assessment questionnaire in inflammatory bowel disease.;Fecal calprotectin level. Timepoint: Before the intervention and 8 weeks after the intervention. Method of measurement: Fecal calprotectin measurement kit.