ISRCTN17837384Completed未知
An acute investigation into the relationship between genetic variation, digestion and blood glucose response upon consumption of carbohydrates
niversity College London (UCL) (UK)0 sites48 target enrollmentStarted: November 6, 2013Last updated:
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 48
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Current inclusion criteria as of 10/03/2014:
- •1. Healthy, non-smoking, men and women aged between 18-40 years old
- •2. British participants who were born in the UK and who have four grandparents that were also born in the UK
- •Previous inclusion criteria:
- •Healthy, non-smoking, men and women, aged 18-40 years, of British ethnicity
Exclusion Criteria
- •Exclusion criteria identified during visit 1 using questionnaire:
- •1. The subject is an employee of Unilever
- •2. Medical history of myocardial infarction, angina, thrombosis, stroke, cancer or diabetes
- •3. Medical history of eating disorders such as anorexia nervosa, bulimia, binge eating disorder
- •4. Medical history of digestive dysfunction, or intestinal disease such as IBS and Crohn?s disease
- •5. Medical history of pancreatitis (Acute, Chronic or Hereditary) and exocrine pancreatic insufficiency
- •6. Alcohol intake exceeding a moderate intake (>28 units per week)
- •7. Needle phobic, fear of blood and blood clotting disorders such as haemophilia
- •8. Pregnant, breast-feeding and post-menopausal women
- •Exclusion criteria identified after visit 2, using genetic and health screening methods:
- •1. Fasting plasma glucose > 6.0 mmol /L
- •2. Fasting plasma insulin > 60 pmol/L
- •3. Fasting plasma cholesterol > 7.8 mmol /L
- •4. Body fat percentage < 8% or >25% for men and < 20% or >35% for women
- •5. Body mass index (BMI) <18.5 or >25.5
- •6. Blood pressure < 90/60 or >120/80
- •7. Abnormal liver function
- •The following will be recorded but are not considered grounds for exclusion, as there is no evidence that this will cause adverse response or distress to the subjects, but it may be of interest.
- •1. Diagnosed lactose intolerance
- •2. Confirmed gluten sensitivity, including coeliac disease
Investigators
Similar Trials
Not yet recruiting
Not Applicable
The investigation of the relationship between the morphology of coronary atherosclerosis and gene information in coronary artery disease patients.Coronary artery disease patientsJPRN-UMIN000047125Kobe University School of Medicine, Division of Cardiovascular Medicine, Department of Internal Medicine50
Recruiting
Not Applicable
Obesity and worsening of chronic venous disease and joint mobilityChronic venous diseaseCardiovascular - Diseases of the vasculature and circulation including the lymphatic systemDiet and Nutrition - ObesityObesityACTRN12610000761066Cleusa Ema Quilici Belczak100
Not yet recruiting
Not Applicable
Prospective investigation of the relationship between plasma cardiac biomarkers(Neprilysin, pro BNP, ANP and BNP) and pathology of patients with chronic heart failureheart failureJPRN-UMIN000026209Cardiovascular Medicine Okayama University Graduate School of. Medicine, Dentistry and Pharmaceutical Sciences140
Not yet recruiting
Not Applicable
A study investigating the possible relation between inter-subject variation in parameters of whole saliva, pellicle and differences in susceptibility to erosiotandweefselweardental erosionNL-OMON32183niversitair Medisch Centrum Groningen50
Completed
Not Applicable
Effect of physiotherapy intervention (exercises) on sleep,pain and neck muscles in chronic neck pain subjectsCTRI/2019/09/021028Jamia Millia Islamia31