IRCT20170830035998N4
Recruiting
Phase 2
Evaluation of the effects of N-Acetyl cysteine on sperm parameters, biochemical-hormonal factors,c hromatin integrity and NRF2 ,HSPA2genes expression in the terato-astenozoospermic men.
Infertility Center of Qom0 sites50 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Terato-Asethenozospermia.
- Sponsor
- Infertility Center of Qom
- Enrollment
- 50
- Status
- Recruiting
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Entry criteria: normal anatomy of the genital area; infertility due to teratology \- asthenospermia wHO2010 criteria
Exclusion Criteria
- •Exclusion Criteria: Genital infection during the study; systemic medication for other infections; intake of dietary supplements 3 months before study; positive history of contact with chemical substances, solvents and inorganic substances; specimens from subjects with known etiology (varicocele, cryptorchidism, urinary tract infection, trauma, chemotherapy and etc.); individuals younger than 20 years or older than 40 years old; Individuals with varicocele; prostatitis; epidimitis; orchidism; mumps; testicular trauma; hyperthyroidism; hypothyroisdism; diabetes; thalassemia major; genetic disorders affecting infertility (Klinefelter , Noonan syndrome , microdeletion of chromosome Y, the mitochondrial DNA mutations); histotry of hernia surgery; vasectomy; consumption of antioxidant drugs
Outcomes
Primary Outcomes
Not specified
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