Evaluation of Cardiac Rehabilitation Functional and Physical Capacity, Health-related Quality of Life and Associations With Frailty in Older Patients After Ischemic Heart Disease and Interventional Treatment
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Frailty Syndrome
- Sponsor
- Lithuanian University of Health Sciences
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Frailty level by Edmonton frail scale score
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of this study is to evaluate functional and physical capacity, health-related quality of life and associations with frailty in older patients after ischemic heart disease and interventional treatment with an individualized physical training program in the second phase of cardiac rehabilitation.
Investigators
Aurelija Beigienė
Aurelija Beigienė, MD
Lithuanian University of Health Sciences
Eligibility Criteria
Inclusion Criteria
- •Patients after acute coronary syndrome and percutaneous coronary intervention or coronary bypass surgery;
- •Age 65 years and older;
- •6-minute walk distance (6-MWD) ≥150 meters;
- •Left ventricular ejection fraction ≥ 40%;
- •Patient's agreement to participate in the study.
Exclusion Criteria
- •combined coronary artery bypass grafting and valve surgery;
- •Cardiac devices;
- •Diseases in the musculoskeletal system or other organs complicating physical activity and exercise training;
- •Exercise-limiting comorbidities (primarily orthopedic and neurological conditions that would exclude individuals from participating in cardiac rehabilitation according to study protocol), cognitive or linguistic deficits.
Outcomes
Primary Outcomes
Frailty level by Edmonton frail scale score
Time Frame: baseline
Frailty measured by The Edmonton frail scale score - 0-3 - fit, 4-5 - vulnerable, 6-7 - mild frailty, 8-9 - moderate frailty,10-17 - severe frailty.
Change from baseline quality of life by MacNew questionnaire
Time Frame: baseline, 3 weeks
The MacNew Heart Disease HRQL questionnaire consists of 27 items which fall into three domains (a 13-item physical limitations domain scale, a 14-item emotional function domain scale, and a 13-item social function domain scale). There are 5 items that inquire about symptoms: angina/chest pain, shortness of breath, fatigue, dizziness, and aching legs. The time frame for the MacNew is the previous two weeks.
Change from baseline functional capacity by six minutes walking test (6MWT)
Time Frame: baseline, 3 weeks
6MWT measured by meters
Change from baseline cardiopulmonary exercise capacity by maximal load (maxWatt)
Time Frame: baseline, 3 weeks
Maximal load measured with spiroergometry by maximal watts
Change from baseline cardiopulmonary exercise capacity by maximal oxygen consumption (peakVO2)
Time Frame: baseline, 3 weeks
PeakVO2 measured with spiroergometry by millilitres of oxygen per kilogram of body mass per minute
Secondary Outcomes
- Change from baseline physical performance by Short Physical Performance Battery (SPPB)(baseline, 3 weeks)
- Change from baseline muscular strength by one repetition maximum test (1RM)(baseline, 3 weeks)