Predicting the successful resolution of Obstructive Sleep Apnoea following weight-loss surgery

Not Applicable

• Conditions: Obstructive Sleep Apnoea; Obesity; Respiratory - Sleep apnoea; Diet and Nutrition - Obesity

• Registration Number: ACTRN12619001505190
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-31
• Study Completion: 2022-09-15
• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

•Ability to consent
•Moderate/severe OSA (Apnoea Hypopnea Index [AHI] > 15)
•Body Mass Index (BMI) of 35-55
•Scheduled to undergo a sleeve gastrectomy surgery for weight-loss
•Patients will be otherwise healthy (except for treated hypertension and diabetes)

Exclusion Criteria

•Untreated medical problems other than OSA
•Patients with safety concerns (drowsy driving within the past 1 year)
•Receiving medication that could affect ventilation (i.e. morphine derivatives, benzodiazepines, theophylline) or muscle control.
•Allergy to lidocaine or oxymetazoline
•Previous surgical treatment for OSA and/or obesity
•Women who are pregnant or breastfeeding

Study & Design

• Study Type: Observational
• Study Design: Not specified