Effect of Peripheral Laser Iridotomy Placement on Post-operative Visual Function

Not Applicable

• Conditions: Glaucoma, Angle-Closure
• Interventions: Procedure: Superior laser peripheral iridotomy; Procedure: Temporal laser peripheral iridotomy

• Registration Number: NCT03352492
• Lead Sponsor: University of the Incarnate Word

Brief Summary

To evaluate the influence of superior versus temporal laser peripheral iridotomy location on post-operative visual acuity and contrast sensitivity.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-11-20
• Study First Submitted QC: 2017-11-20
• Study First Posted: 2017-11-24
• Study Start: 2018-01-01
• Status Verified: 2020-04
• Last Update Submitted: 2020-04-12
• Last Update Posted: 2020-04-14
• Primary Completion: 2021-02
• Study Completion: 2021-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Angle-closure glaucoma
• Angle-closure glaucoma suspect

Exclusion Criteria

• Monocular status
• Previous intraocular surgery
• Visual acuity worse than 20/40
• Prior episode of acute angle-closure glaucoma
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Bilateral iridotomy: Superior	Superior laser peripheral iridotomy	Each subject in this single-arm study undergoes bilateral laser peripheral iridotomy surgery. Each participant will undergo superior laser peripheral iridotomy in one eye and temporal laser peripheral iridotomy in the fellow eye.
Bilateral iridotomy: Temporal	Temporal laser peripheral iridotomy	Each subject in this single-arm study undergoes bilateral laser peripheral iridotomy surgery. Each participant will undergo superior laser peripheral iridotomy in one eye and temporal laser peripheral iridotomy in the fellow eye.

Primary Outcome Measures

Name	Time	Method
Change in visual acuity	30 days post-operative	Change from baseline best corrected visual acuity evaluated in number of letters correctly read on the ETDRS chart

Secondary Outcome Measures

Name	Time	Method
Change in Peli-Robson contrast sensitivity	30 days post-operative	Change from baseline in contrast sensitivity evaluated in number of letters correctly read on the Peli-Robson chart
Change in CSV-1000 contrast sensitivity	30 days post-operative	Change from baseline in contrast sensitivity evaluated using the number of correct responses on the CSV-1000 test

Trial Locations

Locations (1)

University of the Incarnate Word; 🇺🇸 San Antonio, Texas, United States