Effects of Different Coffee Amounts on Energy Intake, Appetite, Glucose Metabolism and Inflammatory Markers

Not Applicable

Completed

• Conditions: Obesity; Inflammation
• Interventions: Other: coffee

• Registration Number: NCT01495754
• Lead Sponsor: Harokopio University

Brief Summary

The purpose of the study is to investigate whether different doses of caffeinated coffee consumption has acute effects on subjective appetite feelings, energy intake and biochemical markers related to appetite, inflammation and glucose metabolism compared to water consumption in normal weight and overweight/obese participants.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Status Verified: 2011-12
• Study First Submitted: 2011-12-16
• Study First Submitted QC: 2011-12-19
• Last Update Submitted: 2011-12-19
• Study First Posted: 2011-12-20
• Last Update Posted: 2011-12-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

• apparently healthy
• habitual coffee drinkers (>= 1cup of coffee/day)

Exclusion Criteria

• smokers
• restrained eaters (as this was evaluated using the Dutch Eating Behaviour Questionnaire)
• those who reported slimming or any other dietary regime
• athletes
• participants with a known diagnosis of either hypertension, diabetes, impaired glucose tolerance or a fasting blood glucose concentration above 125 mg/dl
• subjects on medication for hypertension or on medication known to alter glucose metabolism
• subjects who were on medication that may have an impact on appetite and sensory functioning or who reported a metabolic or
• endocrine disease,
• gastrointestinal disorders,
• a history of medical or surgical events that may have affected the study outcomes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
coffee3	coffee	-
coffee6	coffee	-
water	coffee	-

Primary Outcome Measures

Name	Time	Method
energy intake ad libitum	180 min after breakfast/drink consumption
total energy intake	One day
appetite feelings	180 min after breakfast/drink consumption
appetite hormones	180 min after breakfast/drink consumption
markers of inflammation	180 min after breakfast/drink consumption
markers of glucose metabolism	180 min after breakfast/drink consumption

Secondary Outcome Measures

Name	Time	Method
% carbohydrates ad libitum	180 min after breakfast/drink consumption
% carbohydrates total day	One day
% protein ad libitum	180 min after breakfast/drink consumption
% protein total day	One day
% fat	180 min after breakfast/drink consumption
% fat total day	One day

Trial Locations

Locations (1)

Metabolic Unit of the Department of Nutrition and Dietetics, Harokopio University; 🇬🇷 Athens, Greece