The Clinical Applicability of the 'TIB' Olfactory Test Device
- Conditions
- AnosmiaHyposmia
- Registration Number
- NCT05152030
- Lead Sponsor
- Taichung Veterans General Hospital
- Brief Summary
The aim of this study was to evaluate the validity and test-retest reliability of the 'TIB' Olfactory Test Device, a new olfactory test tool developed by Top International Biotech, Taipei, and to determine its normative values. The olfactory function of 180 subjects was evaluated using both the traditional Chinese version of the University of Pennsylvania of Smell Identification Test (UPSIT-TC) and TIB. The subjects consisted of 60 healthy volunteers (normosmic group), 60 hyposmic patients, and 60 anosmic patients. The healthy volunteers were retested with the UPSIT-TC and TIB at an inter-test interval of at least 7 days. The cut-off scores of TIB among the different groups were determined by receiver operating characteristic curve.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 180
- Normosmic group were self-reported absence of deficits in olfaction. Hyposmic patients were loss of olfactory function with a phenyl ethyl alcohol (PEA) odor detection threshold below -1. Anosmic patients were loss of olfactory function with a PEA threshold equal to -1.
- History of sinonasal symptoms within a week before the test
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method validity of TIB olfactory test 30 minutes to 1 hour Criterion validity: Correlation between UPSIT-TC and TIB olfactory test
Reliability of TIB olfactory test 1 week Test-retest reliability
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Taichung Veterans General Hospital
🇨🇳Taichung, Taiwan
Taichung Veterans General Hospital🇨🇳Taichung, Taiwan