NCT01089868已完成不适用
Quantification of Therapy Effects After Microsurgery, Percutaneous Irradiation and Chemotherapy by FET-PET Analysis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 79
- 试验地点
- 3
- 主要终点
- Overall Survival
研究概览
简要总结
The aim of this study is to establish FET-PET as an additional therapy assessment parameter in patients diagnosed with a glioblastoma multiforme receiving radiochemotherapy and adjuvant chemotherapy after previous resection or biopsy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •neuroradiologically suspected Glioblastoma multiforme
- •histological verification will be obtained either by microsurgery or by stereotactic biopsy. The neuropathological diagnosis will be verified by a reference neuropathologist
- •patients will undergo radiochemotherapy subsequent to surgical procedure
- •patients older than 18 years
- •Karnofsky Performance Score >=70
- •pregnant or nursing female patients will not be included in this study
- •safe contraceptive methods during the radiochemotherapy and chemotherapy
排除标准
- •patients in whom informed consent cannot be obtained due to organic brain syndrome or insufficient language skills
- •patients who cannot lie quiet for a time period of app. two hours during the FET-PEt scan
- •medical history of a metastatic brain disease
- •patients in whom an MRI scan cannot be performed due to claustrophobia metallic protheses or pacemakers etc.
结局指标
主要结局
Overall Survival
时间窗: 46 months
次要结局
- Progression Free Survival(46 months)
研究者
Bogdana Suchorska
PI
Ludwig-Maximilians - University of Munich
研究点 (3)
Loading locations...
相似试验
进行中（未招募）
2 期
Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE StudyAnatomic Stage IV Breast Cancer AJCC v8Hormone Receptor Positive Breast CarcinomaMetastatic Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8NCT04316117ECOG-ACRIN Cancer Research Group138
已完成
3 期
Impact of Positron Emission Tomography Imaging Prior to Liver Resection for Colorectal Adenocarcinoma MetastasesLiver MetastasesColorectal CancerNCT00265356Ontario Clinical Oncology Group (OCOG)404
已完成
不适用
Impact of Positron Emission Tomography (PET) Imaging in Women With Locally Advanced Cervical Cancer (PET LACE Trial)AdenocarcinomaCervical CancerAdenosquamous CarcinomaSquamous Cell CarcinomaNCT00895349Ontario Clinical Oncology Group (OCOG)171
撤回
不适用
Carbon-11 Acetate and Fluorine F 18 Sodium Fluoride PET as a Biomarker of Treatment Response in Patients With Hormone Resistant Metastatic Prostate CancerHormone-resistant Prostate CancerRecurrent Prostate CancerStage IV Prostate CancerNCT02169063University of Washington
招募中
不适用
PET/MR in the Staging and Efficacy Evaluation of Newly Diagnosed NK/T-cell LymphomaNK/T-cell LymphomaNCT05662540Ruijin Hospital40