NL-OMON44108
Completed
Not Applicable
Measuring work-of-breathing in mechanically ventilated children - WOB and paediatric mechanical ventilation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute hypoxaemic respiratory failure
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 48
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •mechanical ventilation for at least 48 hours before the start of weaning
- •weight \>\= 3 kg
- •deemed eligible for weaning by the attending physician
- •stable haemodynamics, defined by the absence of need for increase in vaso\-active drugs and/or fluid challenges at least 6 hours prior to enrolment
Exclusion Criteria
- •mechanical ventilation less than 48 hours for unplanned admissions before the start of weaning
- •post\-operative admission with expected duration of mechanical ventilaton less than 48 hours
- •not eligible for weaning as assessed by the attending physician (usually when there are unstable ventilator settings, defined by the need for increase of inspiratory pressures or positive end\-expiratory pressure, and a FiO2 \> 0\.6 within 6 hours prior to enrolment)
- •unstable haemodynamics, defined by the need for increase in vaso\-active drugs and/or fluid challenges within 6 hours prior to enrolment
- •admitted to the neonatal intensive care unit
- •premature birth with gestational age corrected for post\-conceptional age less than 40 weeks
- •congenital or acquired neuromuscular disorders
- •congenital or acquired central nervous system disorders with depressed respiratory drive
- •severe traumatic brain injury (i.e. Glasgow Coma Scale \< 8\)
- •congenital or acquired damage to the phrenic nerve
Outcomes
Primary Outcomes
Not specified
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