PET-CT Based Radiotherapy in Esophageal Cancer Patients

Completed

• Conditions: Esophageal Neoplasms

• Registration Number: NCT01156831
• Lead Sponsor: Maastricht Radiation Oncology

Brief Summary

The purpose of this study is to determine the locoregional control in PET/CT based radiotherapy treatment planning in the treatment of esophageal cancer patients.

Detailed Description

The purpose of this study is to determine the locoregional control in PET/CT based radiotherapy treatment planning in the treatment of esophageal cancer patients

Study Timeline

• Study Start: 2007-11
• Study First Submitted: 2010-07-02
• Study First Submitted QC: 2010-07-02
• Study First Posted: 2010-07-05
• Primary Completion: 2011-05
• Study Completion: 2013-05
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-05
• Last Update Posted: 2014-12-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 115

Inclusion Criteria

• Histologically proven adenocarcinoma or squamous cell carcinoma of the esophagus
• Local curable disease able to undergo Chemoradiotherapy.

Exclusion Criteria

• Metastasized disease.
• Previous or concurrent malignancies.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Locoregional control	2 years and 5 years

Secondary Outcome Measures

Name	Time	Method
Overall Survival	2 years and 5 years
Disease Free survival	2 years and 5 years
Tumor regression grade	At the time of surgery	Tumor regression grade at time of surgery evaluated by pathologist.

Trial Locations

Locations (5)

Atrium Hospital; 🇳🇱 Heerlen, Netherlands

University Medical Center; 🇳🇱 Maastricht, Netherlands

Maasland Hospital; 🇳🇱 Sittard, Netherlands

St. Jansgasthuis; 🇳🇱 Weert, Netherlands

St. Laurentius Hospital; 🇳🇱 Roermond, Netherlands