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临床试验/NCT00901602
NCT00901602招募中不适用

Lebanese Interhospital Pneumococcal Surveillance Program (LIPSP)

American University of Beirut Medical Center1 个研究点 分布在 1 个国家目标入组 700 人开始时间: 2005年10月最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
700
试验地点
1
主要终点
Serotype prevalence of S. pneumoniae in invasive pneumococcal disease

研究概览

简要总结

Streptococcus pneumoniae (pneumococcus) is a bacterium that causes severe infections in children and adults such as meningitis, pneumonia, and blood stream infection. There are many types of these bacteria defined by the type of sugar coat that they have. These are classified as serotypes. There are common serotypes that cause severe disease and are preventable by vaccination of children. Other less common types are more difficult to prevent. The investigators aim to determine the serotypes that cause invasive pneumococcal disease in Lebanon and to study their sensitivity to different antibiotics. The investigators will collect bacterial isolates from different hospitals in Lebanon isolated from the blood or spinal fluid of patients with invasive pneumococcal disease. This information will help the investigators determine the usefulness of available pneumococcal vaccines in preventing these infections. The data will be distributed to all primary care physicians treating children in Lebanon and will be shared with the Ministry of Health.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
1 Day 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Samples included in the study are those that are:
  • culture proven
  • invasive pneumococcal infections
  • in patients of all ages admitted to different hospitals all over Lebanon
  • Acceptable samples include:
  • positive isolates from blood
  • cerebrospinal fluid
  • other normally sterile body sites such as empyema fluid, abscesses, joint fluid, middle ear fluid obtained by tympanocentesis in the operating room, and lung needle aspiration

排除标准

  • non S. pneumoniae isolates

结局指标

主要结局

Serotype prevalence of S. pneumoniae in invasive pneumococcal disease

时间窗: yearly

次要结局

  • Determine the antibiotic sensitivity of S. pneumoniae and the association with specific serotypes(yearly)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Ghassan Dbaibo

Professor

American University of Beirut Medical Center

研究点 (1)

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