Effects Of Bobath Exercises Combined With Gasotransmitter On Spastic Diplegic CP
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Gross Motor Function Classification System (GMFCS)
研究概览
简要总结
This study examines the effects of combining Bo bath neurodevelopmental exercises with gasotransmitter in children with spastic diplegic cerebral palsy, a condition marked by muscle stiffness and coordination challenges in the legs.
详细描述
The primary objective is to enhance motor learning by reinforcing weak movement patterns while reducing excessive muscle activity. Additionally, this combination aims to improve postural control, movement coordination, and overall functional abilities.The randomized controlled trial includes 47 children aged 6-18, divided into three groups: one receiving only Bo bath exercises, another receiving gasotransmitter alone, and a third receiving both interventions. Baseline assessments were conducted, and ethical approval along with informed consent was obtained. The interventions target spasticity reduction and gross motor improvement, with outcomes measured using the Gross Motor Function Classification System (GMFCS) for motor skills and the Modified Ashworth Scale for spasticity. Findings suggest that combining Bo bath therapy with gasotransmitters effectively reduces spasticity, enhances motor control, and supports activities of daily living, highlighting its potential as an effective therapeutic approach.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A Confirmed diagnosis of spastic diplegic cerebral palsy
- •Participants aged 6 to 18 years.
- •Moderate to severe spasticity in the lower limbs, as measured by the Modified Ashworth Scale.
- •Ability to follow simple instructions and participate in the stretching exercises.
- •Written informed consent obtained from the participant's legal guardian or the participant if of legal consenting age.
- •No significant changes in medication or therapy for cerebral palsy in the three months prior to the study.
排除标准
- •Presence of other neurological conditions apart from spastic diplegic cerebral palsy.
- •History of major orthopaedic surgery in the past year or planned surgery during the study period.
- •Receipt of botulinum toxin injections in the lower limbs within the last six months.
- •Severe joint contractures that limit the range of motion necessary for the stretching exercises.
- •Any medical condition that contraindicates participation in the study, such as uncontrolled epilepsy, severe cardiovascular disorders, or acute infections.
- •Inability or unwillingness to comply with the study protocol and scheduled visits.
研究组 & 干预措施
Bobath exercises
干预措施: Bobath exercises (Diagnostic Test)
Gasotransmitters
干预措施: Gasotransmitters (Combination Product)
结局指标
主要结局
Gross Motor Function Classification System (GMFCS)
时间窗: 12 Months
The Gross Motor Function Classification System (GMFCS) is a five-level clinical classification tool that categorizes the gross motor function of children and young people with cerebral palsy (CP) based on their self-initiated movement abilities, particularly sitting, walking, and mobility. The GMFCS is used to understand and predict the mobility needs and functional capabilities of individuals, aiding in treatment planning, goal setting, and tracking functional changes over time.
Manual Muscle Testing Manual Muscle Testing (MMT)
时间窗: 12 months
It is a clinical assessment technique used to evaluate and grade the strength of individual muscles or muscle groups based on their ability to resist force. In MMT, the clinician applies pressure to a muscle while the patient resists, allowing for a standardized rating, typically on a scale from 0 to 5:
次要结局
未报告次要终点
研究者
Muhammad Naveed Babur
Principal Investigator
Superior University