Development of a Mass-spectometry Based Method for Detecting Xenon Application in Humans
- Conditions
- Anesthesia
- Interventions
- Drug: Anesthesia with inhalative application of xenon gas
- Registration Number
- NCT02105077
- Lead Sponsor
- Heinrich-Heine University, Duesseldorf
- Brief Summary
The purpose of this study is to establish a laboratory method to determine from blood samples whether a person has been treated with xenon.
- Detailed Description
The noble gas xenon is used for general anesthesia in clinical routine. Recent reports indicate that xenon is also used for increasing performance in high-performance sports. The purpose of this study is to establish a method for detecting xenon exposure in humans.
In patients undergoing surgery with xenon anesthesia as part of routine hospital care, small blood samples (3ml) will be taken before anesthesia, during anaesthesia and at 1,2, 4, 8, 16, 24, 32, 40 and 48 hours after anesthesia. These blood samples will be analyzed for traces of xenon.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 8
- Age of 18 years and older
- Xenon-based anesthesia as part of routine care
- Inability to give written informed consent
- Known pregnancy
- Hemoglobin concentration of less than 12g/dl
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Xenon Anesthesia with inhalative application of xenon gas Patients undergoing surgery with xenon-based general anesthesia
- Primary Outcome Measures
Name Time Method Detection of xenon in patient blood sample by mass spectrometry 24 hours after xenon anesthesia
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Klinik für Anästhesiologie, Universitätsklinikum Düsseldorf
🇩🇪Düsseldorf, Germany