Walking Program in Fatty Liver Children With Phenylketonuria

Not Applicable

Recruiting

• Conditions: Phenylketonurias; Non Alcoholic Fatty Liver

• Registration Number: NCT06718842
• Lead Sponsor: Cairo University

Brief Summary

phenylketonuria (commonly known as PKU) is an inherited disorder that increases the levels of a substance called phenylalanine in the blood. PKU is usually associated with many metabolic complication including non-alcoholic fatty liver

Detailed Description

this study will include PKU children sufferers 9n=40) with non-alcoholic fatty liver to be randomly assigned to group I (n=20) that will perform walking program (online supervised free walking that will be applied daily for eight weeks) or group II (N=20) that will act as waitlisted children

Study Timeline

• Study Start: 2024-09-15
• Status Verified: 2024-12
• Study First Submitted: 2024-12-02
• Study First Submitted QC: 2024-12-02
• Last Update Submitted: 2024-12-02
• Study First Posted: 2024-12-05
• Last Update Posted: 2024-12-05
• Primary Completion: 2025-01-30
• Study Completion: 2025-01-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• PKU children
• obese children
• fatty liver children (non-alcoholic fatty liver)

Exclusion Criteria

• cardiac children
• diabetic children
• neurogenic disorders
• respiratory and renal problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
alanine transamianse	it will be assessed after eight weeks	it is a serum liver enzyme

Secondary Outcome Measures

Name	Time	Method
aspartate tranaminase	it will be assessed after eight weeks	it is a serum liver enzyme
Gamma-glutamyl Transferase	it will be assessed after eight weeks	it is a serum liver enzyme
alkaline phosphatase	it will be assessed after eight weeks	it is a serum liver enzyme
triglycerides	it will be assessed after eight weeks	it will be measured in the serum
body mass index	it will be assessed after eight weeks	it will be measured after emptying bladder

Trial Locations

Locations (1)

Cairo University; 🇪🇬 Dokki, Giza, Egypt