The effects of a chiropractic care in recent stroke patients - Study 2/2

Not Applicable

Completed

• Conditions: Stroke; Stroke - Ischaemic; Stroke - Haemorrhagic

• Registration Number: ACTRN12616000825459
• Lead Sponsor: ew Zealand College of Chiropractic

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-23
• Study Completion: 2019-02-28
• Last Update Posted: 16 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

20-25 participants will be recruited to participate in each of these studies. Participants will be inpatients or outpatients at Shifa International Hospital, in Islamabad or Railway Hospital, Rawalpindi, Pakistan. To be eligible to participate volunteers must have suffered from a stroke at least 12 weeks prior to their involvement in the trial and have some ongoing neurological deficit. For the study they must have some ongoing neurological deficit but this deficit may not be in the lower limb.

Exclusion Criteria

Volunteers will be ineligible to participate if they exhibit no evidence of spinal dysfunction, have absolute contraindications to spinal manipulation, have experienced previous significant adverse reactions to chiropractic care, or if they are deemed unsuitable to receive chiropractic care by their treating physicians.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In this second study the primary objectives is to use somatosensory evoked potentials (SEP) to:<br>Investigate which brain areas are involved in processing somatosensory information in a stroke population.<br>[Immediately pre and post spinal manipulation session and immediately pre and post control intervention.<br>];Spatio-spectral power in the resting-state EEG. For this classical frequency band (delta (1-4 Hz), theta (4.1-8 Hz), alpha (8.1-12 Hz), beta (12.1-32 Hz), and gamma (32.1-80 Hz)) will be used.[Immediately pre and post spinal manipulation session and immediately pre and post control intervention.]

Secondary Outcome Measures

Name	Time	Method
The secondary outcome is to use somatosensory evoked potentials to study what changes occur with in the brain structures,calculated using source localization methods of the SEPs and resting EEG .[Immediately pre and post spinal manipulation session and immediately pre and post control intervention.<br>];A further outcome is Brain Source Identification (EEG):<br>Brain sources of SEPs recorded n the scalp reflective upstream activation of brain activity in different centres. Brain sources are identified by inverse modelling of the evoked brain activity. [Post recording]