NL-OMON55574CompletedNot Applicable
Protein-specific turnover in the human brain; Measuring protein-specific synthesis rates of the human brain using the D2O dosing method - D2O in Brain
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- niversiteit Maastricht
- Enrollment
- 12
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •* Written informed consent
- •* Male and female patients scheduled for temporal lobectomy
- •* Age 18 - 65 years
- •* Compos mentis
Exclusion Criteria
- •* Comorbidities and neuromuscular disorders of the lower limbs severely
- •interacting with mobility, with limited or no opportunity for improvement (e.g.
- •cerebral palsy)
- •* Peripheral artery disease Fontaine III or IV
- •* Chronic Obstructive Pulmonary Disease (COPD) GOLD III or IV
- •* Use of systemic steroids in the past four weeks, other than indicated for the
- •specific type of surgery
- •* Use of anti-inflammatory biologicals (e.g. TNF-alfa blockers) in the past
- •* Surgical intervention in the past four weeks
- •* Total parenteral nutrition at day of surgery
- •* Pregnancy
- •* Neoadjuvant chemotherapy or radiotherapy
Investigators
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