Predictors of the Metabolic Effect of Sleep Loss

Not Applicable

Completed

• Conditions: Apnea; Obstructive Sleep Apnea (OSA); Obesity

• Registration Number: NCT00965783
• Lead Sponsor: University of Chicago

Brief Summary

To test whether baseline levels of slow wave activity (SWA) during sleep are lower in obese adults, and even lower in persons with sleep disordered breathing (SDB) compared to lean adults.

To compare levels of SWA in individuals in relation to their sleep time, blood pressure, heart rate, and markers of glucose metabolism.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-06
• Study First Submitted: 2009-08-25
• Study First Submitted QC: 2009-08-25
• Study First Posted: 2009-08-26
• Primary Completion: 2009-12
• Study Completion: 2009-12
• Status Verified: 2013-09
• Last Update Submitted: 2013-09-04
• Last Update Posted: 2013-09-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• healthy,
• normal sleepers,
• lean, overweight,
• obese,
• pre menopausal

Exclusion Criteria

• no shift workers or night-shift workers,
• no mental health disorders,
• no acute or chronic health conditions (stable, well controlled hypertension are accepted),
• no hormonal treatments,
• no substances that may interfere with sleep,
• problems with sleep

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Correlation between SWA, sleep duration,sleep architecture, and biomarkers of the metabolic syndrome in lean, obese with and without obstructive sleep apnea.	study completion

Trial Locations

Locations (1)

The University of Chicago; 🇺🇸 Chicago, Illinois, United States