A study to investigate the effects of voluntary coughing on the airways of asthmatic and COPD subjects
Not Applicable
Completed
- Conditions
- RespiratoryRespiratory: Chronic obstructive pulmonary disease (COPD)Chronic obstructive pulmonary disease (COPD)
- Registration Number
- ISRCTN57141601
- Lead Sponsor
- Record Provided by the NHSTCT Register - 2007 Update - Department of Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Aged over 18
2. Physician diagnosed asthma or COPD
Exclusion Criteria
1. Symptoms of upper respiratory tract infection or asthmatic/COPD exacerbation in the preceding 4 weeks
2. Involved in studies with licensed drugs or methodological studies within the preceding 4 weeks
3. Subjects taking ACE inhibitors, leukotrine receptor antagonists or cough suppressants
4. Change in asthma/COPD medication in last 4 weeks
5. Pregnancy
6. Current smokers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The fall in exhaled nitric oxide (eNO) following voluntary coughing.
- Secondary Outcome Measures
Name Time Method o secondary outcome measures