Transplantation of immunoprotected pancreatic islets for the therapy of type 1 diabetes mellitus (T1DM)

Completed

• Conditions: Type 1 diabetes mellitus; Nutritional, Metabolic, Endocrine; Insulin-dependent diabetes mellitus

• Registration Number: ISRCTN43557935
• Lead Sponsor: niversity of Perugia (Italy)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-06-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

1. Male patients, age range: 20-50 years
2. Patients with long-standing T1DM (over 15 years)
3. On daily quadruple insulin injection therapy regimen
4. No major complications of the disease (pre-proliferative retinopathy, initial microalbuminuria, macrovascular disease)

Exclusion Criteria

1. Female patients (because the capsules were to be implanted intraperitoneally, with possible adverse effects on ovary's function)
2. Patients with advanced complcations of T1DM
3. Patients with neoplasms whatsoever

Study & Design

• Study Type: Interventional
• Study Design: Not specified