CTRI/2012/11/003120招募中3 期
Randomised trial of pulsed Actinomycin D versus MTX infusion in low risk gestational trophoblastic neoplasia
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Patients with abnormal hCG regression following any type of pregnancy (molar, term, abortion,ectopic) ie
- •(1)hCG plateau for 4 consecutive values over 3 weeks
- •(2)hCG rise of >10% for 3 values over 2 weeks
- •(3)hCG persistence 6 months after molar pregnancy evacuation
- •For staging and pretreatment evaluation, all patients will undergo complete physical and pelvic examination, complete blood cell count, urinalysis, liver and renal function tests, and chest x-ray. Ultrasonography and/or computed tomographic scanning will be performed when clinically indicated. Diagnosis, staging, and risk scoring will be as per International Federation of Gynecology and Obstetrics (FIGO) 2000 criteria for diagnosis and staging for GTN.
- •Low risk gestational trophoblastic disease FIGO score <6
排除标准
- •Choriocarcinoma
- •Any patient with renal, hepatic,haematological disease
- •Prognostic score > 6
研究者
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