Investigation of the effect of oak extract (quercus) on nausea reflex
Phase 3
Recruiting
- Conditions
- Gag reflex.Nausea and vomiting
- Registration Number
- IRCT20130211012438N33
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
History of gag experience in dentistry
Exclusion Criteria
1- Existence of any type of central and peripheral nerve lesions
Existence of any type of oral lesions
Taking any medicine
Suffering from gastrointestinal and respiratory diseases
Allergy to medicinal plants
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gag reflex. Timepoint: Before examination and 5 minutes after using candies containing oak and placebo extracts. Method of measurement: Before and 5 minutes after sampling by Abslang. Criteria for measuring the severity of nausea: No nausea: No gag during contact with high risk surfaces of the mouth such as soft palate and tonsils Hakm: Gag formation during contact with high risk surfaces of the mouth such as soft palate and tonsils Medium: Gag formation during contact with low levels Risk of mouth such as hard palate and hard floor: Creating a gag before contact with an abscess, such as when opening the mouth and seeing an abscess.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does quercus extract modulate to suppress gag reflex and nausea in dental patients?
How does quercus extract compare to standard antiemetics like ondansetron in managing gag reflex during dental procedures?
Are there specific biomarkers that predict enhanced efficacy of quercus extract in suppressing nausea reflex in phase III trials?
What are the potential adverse events associated with quercus extract administration in phase III clinical trials for gag reflex suppression?
What are the current combination therapies or competitor drugs being evaluated for managing gag reflex and nausea in dental settings?