Cognitive decline and brain structural alterations caused by metabolic dysfunction in older adults with type 2 diabetes: a prospective observational study. - Cognitive decline and brain structural alterations caused by metabolic dysfunction in older adults with type 2 diabetes: a prospective observational study.

Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology.0 sites100 target enrollmentOctober 26, 2020

Overview

Phase: N/A
Intervention: Not specified
Conditions: Not specified
Sponsor: Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology.
Enrollment: 100
Status: Completed
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

No summary available.

Registry

who.int

Start Date

October 26, 2020

End Date

December 31, 2023

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology.

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•Subjects who 1\) are diagnosed with type 1 diabetes mellitus. 2\) are diagnosed with dementia. 3\) are unable to perform cognitive tests. 4\) use implanted medical devices, such as pacemakers. 5\) decreased cognitive function due to Parkinson's disease, apoplexy, Huntington's disease, normal pressure hydrocephalus, brain tumors, progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, aphasia, epilepsy, subdural hematoma, encephalitis/meningitis, multiple sclerosis, or head injury. 6\) have any local lesion, such as cerebral infarction(s) detected by CT or MRI before enrollment, that may greatly affect cognitive function. 7\) have a history of major depression, bipolar disorder, schizophrenia, or alcohol/drug abuse; have current serious or unstable disease. 8\) unsuitable for treatment due to vitamin B1/B12 and/or folate deficiency, or thyroid dysfunction 9\) are deemed ineligible for enrollment by the responsible researcher or co\-researcher.