The Therapeutic Effect and Standardization of Moxibustion in the Treatment of Allergic Rhinitis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Total nasal symptom scores（TNSS）
研究概览
简要总结
The objective of this randomized controlled clinical trial is to compare the therapeutic effect of moxibustion on allergic rhinitis. The main questions it aims to answer are:
Based on randomized controlled trials, verify the effectiveness of moxibustion in treating allergic rhinitis Based on a real-time monitoring system for human surface temperature, discuss the differences in therapeutic effects of different moxibustion doses on allergic rhinitis
详细描述
Allergic rhinitis has a high incidence and is difficult to cure, seriously affecting the quality of life of patients Compare the effects of different moxibustion durations on the clinical efficacy and body surface temperature of patients with allergic rhinitis, and preliminarily explore the impact of different moxibustion doses on the efficacy of heavy moxibustion treatment for allergic rhinitis, providing evidence-based basis for clinical practice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Those who meet the diagnostic criteria of Chinese and Western medicine for AR;
- •Age range from 18 to 75 years old, regardless of gender;
- •Patients and their families are informed and agree to the study.
排除标准
- •Those who are undergoing other traditional Chinese medicine external treatment methods;
- •Those who have taken traditional Chinese medicine recently or during treatment;
- •Individuals who are allergic to heavy moxibustion smoke and dust;
- •Individuals with concomitant bronchial asthma or other respiratory system diseases;
- •Patients with severe skin diseases or ulcers in the local area where moxibustion is applied;
- •Pregnant and lactating patients;
- •Patients with severe diseases of important organs such as the heart, liver, lungs, and kidneys;
- •Those who are unable to receive treatment according to regulations due to inconvenience in work, study, transportation, or personal activities
结局指标
主要结局
Total nasal symptom scores（TNSS）
时间窗: Change from baseline TNSS scores at week 0(before treatment)，4 and 12.
The main symptoms of allergic rhinitis, the higher the score, the worse the condition
Rhinitis VAS Visual Analog Scale（AR-VAS）
时间窗: Change from baseline VAS scores at week 0(before treatment)，4 and 12.
VAS will be used to evaluate the relief of rhinitis symptoms, with a total score of 0-10. The higher the score, the more severe the symptoms will be
次要结局
- Total non nasal symptom scores（TNNSS）(Change from baseline TNNSS scores at week0(before treatment)，4 and 12.)
- Detection of serum IgE and IL-33 levels(Week0(before treatment), week 4（after treatment）.)
- Rhino-conjunctivitis Quality of Life Questionnaire （RQLQ）(Change from baseline RQLQ scores at week0(before treatment)，4 and 12.)