NL-OMON37755尚未招募不适用
Brown adipose tissue activity in lung cancer - Brown adipose tissue activity in lung cancer
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 13 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 13
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Resectable non-small cell lung cancer (NSCLC)
- •Age 40-70 years
- •Gender: male and female
- •Non-obese persons, i.e. Body Mass Index (BMI) <30 kg/m2
排除标准
- •Body Mass Index > 30 kg/m2
- •Medically treated Diabetes mellitus (oral anti-diabetics, insulin)
- •Severe COPD and/or heart failure
- •Patients with severe clotting disorder
- •Patients with a second malignancy, either active or in previous medical history
- •Thyroid disorders
- •Psychological unstable persons presumed unfit to perform the measurements, including claustrophobia
- •Patients with shortness of breath in rest
- •Persons unable to lie or sit still for1-2 hours
- •Pregnant subjects
- •Subjects that received high doses of radiotherapeutic radiation of the neck and/or upper chest in their medical history
- •Persons that received cervical of thoracic sympathectomy or have a nerve dysfunction which is likely to influence sympathetic nerves
- •The use of the medication that influences the sympathetic nerve system: ß-blockers, a-blockers, central anti-hypertensives, certain anti-depression drugs (MAO inhibitors, tricyclic anti-depressives) reserpine, cocaïne, calciumblockers, labetalol, certain tranquillizers (fenothiazines)
- •Exclusion criteria for core temperature measurement:
- •-In any patient whose body weight is less than 40 kg
- •-In the presence of any known or suspected obstructive disease of the gastrointestinal tract
- •-In any patient exhibiting or having a history of disorders or impairment of the gag reflex
- •-In any patient with previous gastrointestinal surgery
- •-In any patient having structural and/or functional disorders of the esophagus
- •-In any patient who might undergo Nuclear Magnetic Resonance (NMR) or MRI scanning during the period that the CorTemp* Disposable Temperature Sensor is within the body.
- •-In any patient with hypo motility disorders of the gastrointestinal tract
- •-In any patient having a cardiac pacemaker or other implanted electro medical device.;Secondary
- •Unsuccesful complete macro- and microscopic resection of the lung tumor
- •Presence of tumor recurrence on the second PET-CT scan
研究者
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