A comparative study on the efficacy and dermoscopic changes in 1064 nm Q Switched Nd-YAG laser versus glycolic acid peel in Macular Amyloidosis
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Color score will be used before and 1 month after the treatment in both the groups
研究概览
简要总结
This study is a randomized, open label, comparative study on the efficacy and dermoscopic changes in 1064 nm Q switched Nd-YAG laser and glycolic acid peel in macular amyloidosis that will be conducted in a tertiary care center in India. The primary outcome will compare the color score which will be used before and 1 month after the treatment in both the groups. The secondary outcomes will be Visual Analogue Score - will be done before and 1 month after completion of treatment,
dermoscopic findings before and 1 month after completion of treatment and subjective improvement 1 month after completion of treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged ≥18 years of either sex, Patients with macular amyloidosis,Patients who are not on any topical/oral/laser therapy for last 01 month, Patients with written informed consent by self or by guardian.
排除标准
- •Patient with history of any treatment for macular amyloidosis in last 01 month, Pregnant females, Photosensitive dermatoses, Patients with known hypersensitivity to chemical peels, Patients with unrealistic expectations, Patients will be dropped from the study if any adverse effect noticed after test patch.
结局指标
主要结局
Color score will be used before and 1 month after the treatment in both the groups
时间窗: 6 months
次要结局
- VAS (Visual Analogue Scale) - Will be done 1 month after completion of treatment(6 months)
- Dermoscopic findings(6 months)
- Subjective improvement(6 months)
研究者
Dr. Gulshan Kumar Sirohi
Command Hospital Air Force Bangalore