The study of the diagnostic agreement between qualitative diagnosis by using endocytoscopy and pathological diagnosis by using biopsy in colon polyps.
- Conditions
- colon polyps
- Registration Number
- JPRN-UMIN000023738
- Lead Sponsor
- Gatrointestinal Center, Sano Hospital
- Brief Summary
A total of 39 patients with 63 diminutive polyps were analyzed. All polyps were evaluated by endocytoscopy. The mean polyp size was 3.3 mm. Among the 63 diminutive polyps, 60 were flat and 3 were pedunculated. The mean time required for endocytoscopic observation, including the time for staining with crystal violet and methylene blue, was 3.0 min. Histopathologic evaluation showed that 13 polyps were hyperplastic and 50 were adenomas. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of EC2 for adenoma compared with EC1b for hyperplastic polyp were 98.0%, 92.3%, 96.8%, 98.0% and 92.3%, respectively. There were only two cases of disagreement between the endoscopic diagnosis made by endocytoscopy and the corresponding histopathological diagnosis..
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
1.patients with a history of inflammatory bowel disease, hereditary polyposis syndrome, or Lynch syndrome 2. patients with poor bowel preparation 3. patients without polyps 4. polyps detected after three polyps was observed by endocytoscopy in a patient 5. polyps whose histopathology had not been evaluated 6. polyps which have possibility of cancer on conventional endoscopy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The diagnostic agreement between diagnosis by endocytoscopy and pathological diagnosis by biopsy in colon polyps.
- Secondary Outcome Measures
Name Time Method The proportion of cases in which the lesions are observed clearly by endocytoscopy. Time needed in endocytoscopy.