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Effect of serum on fibroblasts and macrophages in patients with primary liver cancer before and after TACE and the effect of Jiedu recipe

Phase 1
Conditions
Primary liver cancer
Registration Number
ITMCTR2200005664
Lead Sponsor
Shanghai Changhai Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) Patients with primary liver cancer diagnosed according to the diagnostic and therapeutic specifications for primary liver cancer (2019 Edition) are classified as stage B in Barcelona;
(2) Patients should not receive any Chinese herbal medicine and systemic treatment in the past two weeks;
(3) ECoG (Eastern Cooperative Oncology Group) score 0-1;
(4) Compensatory liver function, or child Pugh grade A or B;
(5) Patients need a life expectancy of at least 3 months;
(6) Voluntarily accept the treatment of this study protocol and sign the informed consent form.

Exclusion Criteria

(1) Taking drugs that may affect the evaluation observation indexes during the trial;
(2) The child Pugh score of liver function was grade C;
(3) WBC < 2.0 × 10 ^ 9 / L, platelet < 30 × 10^9/L
(4) Tumors accounted for more than 70% of the whole liver;
(5) Patients with serious primary diseases such as cardio cerebrovascular, liver, kidney and hematopoietic system and psychosis;
(6) Those who fail to take drugs according to the regulations after informed consent, cannot judge the curative effect, or incomplete data affect the judgment of curative effect.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
PFS;
Secondary Outcome Measures
NameTimeMethod
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