Evaluation of montelukast efficacy on clinical and FEV1/PEFR improvement in acute basthma attack
Phase 3
- Conditions
- Acute attack asthma.Asthma
- Registration Number
- IRCT2015092215446N5
- Lead Sponsor
- Vice chanceller for research, Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
age above 18 years old; documented asthmatic patients with spiropmetry. Exclusion criteria: no response to therapy; use of epinephrine or MgSO4 or IPPV during treatment; patient refuse from continue of treament; lung diseases like ILD; cigarrete smoking.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical state. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Base on alert status, talking, wizing, use of respiratory mu.;Forced Expiratory Volum in First Secend (FEV1). Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.;Peak Expiratory Flow Rate(PEFR). Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Mililiter with use of Peak Flow Meter.
- Secondary Outcome Measures
Name Time Method Blood pressure. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: mmHg.;Pulse Rate. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Rate/Minutes.;Respiratory Rate. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: Rate/Minutes.;Saturation of arterial blood oxygen (SO2 %). Timepoint: Before intervention, 30, 60, 90, 150minutes after intervention. Method of measurement: Pulse Oximetry.;Pulsus Paradox. Timepoint: Before intervention, 30, 60, 90, 150 minutes after intervention. Method of measurement: 10 mmHg reduction of blood pressure during inspiration.