NCT01007500已完成4 期
Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 123
- 试验地点
- 1
- 主要终点
- Incidence of postoperative nausea and vomiting
研究概览
简要总结
The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing video-assisted thoracoscopic surgery
- •Age 20-75
- •American Society of Anesthesiologists physical status classification I or II
排除标准
- •Antiemetic within 24 hrs
- •Taking Steroids, Opioids within 1 week
- •Active drug or alcohol abuse
- •GI motility disorder, severe renal/ hepatic disease.
研究组 & 干预措施
Group Ondansetron
Active Comparator
干预措施: Ondansetron (Drug)
Group Dexamethasone
Experimental
干预措施: Dexamethasone (Drug)
结局指标
主要结局
Incidence of postoperative nausea and vomiting
时间窗: within 48 hrs after surgery
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
招募中
4 期
Survey the effect of adding dexamethasone to ondansetrone or metoclopramide to increase the effect of these drugs in prevention of nausea and vomiting after caesarian section under spinal anesthesiaIRCT20221127056627N1Shiraz University of Medical Sciences150
已完成
2 期
The comparison of three drugs, Ondnasetrone, Dexametasonel and Magnesium SulfateShivering.Complications of surgical and medical care, not elsewhere classifiedT80-T88IRCT2012100510340N7Golestan university of medical sciences90
招募中
3 期
prophylactic effects of ondansetron with dexamethasone and metoclopramide with dexamethasone on spinal anesthesia complications in caesarean section; a double blind clinical trial studyIRCT20210403050823N1Khalkhal University of Medical Sciences120
已完成
4 期
Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and VomitingPostoperative Nausea and VomitingNCT01876290Hopital Foch122
已完成
不适用
Effect of combined dexamethasone-ondansetrone versus dexamethasone and ondansetrone alone for the prevention of nausea and vomiting after outpatient gynecological diagnostic laparoscopyausea and Vomiting.Other complications of spinal and epidural anaesthesia during labour and deliveryIRCT2014012511700N3Tabriz University of Medical Sciences105