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Clinical Trials/NCT05670366
NCT05670366
Completed
Not Applicable

Proof-of-concept Study for the Integration of Physical Activity Into the Clinical Decision Process of Physically Active People with Type 1 Diabetes

prof dr Pieter Gillard1 site in 1 country33 target enrollmentSeptember 26, 2022
ConditionsType 1 Diabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 1 Diabetes
Sponsor
prof dr Pieter Gillard
Enrollment
33
Locations
1
Primary Endpoint
Database which contains insulin data (insulin dose over time) retrieved from diabetes management platforms.
Status
Completed
Last Updated
last year

Overview

Brief Summary

Every person with type 1 diabetes needs personalized advice to integrate physical activity into daily diabetes management. The purpose of this study is to collect data on food intake, physical activity, glucose levels and insulin delivery from people with type 1 diabetes who are physically active. At least 25 people with type 1 diabetes will be asked to perform 25 sports activities of at least half an hour, wear an activity tracker (day and night) and chest strap (during sports activities), and log data on food intake, periods and type of physical activity, and feelings (e.g., sick, stress) in a diary app. Diabetes data such as insulin administration and sensor data will be collected through diabetes management platforms. The primary endpoint involves a database containing data on glucose, insulin administration, physical activity, and food intake of people with type 1 diabetes for statistical analyses and visualizations regarding the relationship between physical activity and blood glucose response.

Registry
clinicaltrials.gov
Start Date
September 26, 2022
End Date
July 31, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
prof dr Pieter Gillard
Responsible Party
Sponsor Investigator
Principal Investigator

prof dr Pieter Gillard

Principal investigator

Universitaire Ziekenhuizen KU Leuven

Eligibility Criteria

Inclusion Criteria

  • Signed informed consent
  • 18-80 years old
  • Type 1 diabetes ≥1 year
  • Using a CGM for more than 6 months
  • Using insulin (insulin pens, insulin pumps or hybrid closed-loop systems) to manage glycaemia for more than 6 months
  • No use of adjunctive therapies, such as SGLT2-inhibitors or GLP-1 analogues
  • No known diabetic gastroparesis
  • HbA1c of the last two diabetes consultations are both \<10%
  • Being physically active at least twice a week on two separate days for 30 consecutive minutes

Exclusion Criteria

  • Age \<18 years or \>80 years
  • People with type 2 diabetes, people with secondary diabetes
  • Begin treatment with insulin (insulin pens, insulin pumps or hybrid closed-loop systems) less than 6 months before inclusion
  • Not using CGM prior to inclusion
  • Known diabetic gastroparesis
  • HbA1c \> 10% during one of the last two diabetes consultations
  • Not willing to use an activity tracker, the diary app or the food app
  • Not being physically active on a regular basis

Outcomes

Primary Outcomes

Database which contains insulin data (insulin dose over time) retrieved from diabetes management platforms.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains physical activity data (intensity of activity) retrieved from the activity tracker and chest strap.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains food intake data (timing of food) retrieved from the diary app.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains glucose data (glycemic values over time) retrieved from diabetes management platforms.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains food intake data (amount of food in grams) retrieved from the diary app.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains physical activity data (type of activity) retrieved from the activity tracker and chest strap.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains physical activity data (duration of activity) retrieved from the activity tracker and chest strap.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Database which contains food intake data (type of food) retrieved from the diary app.

Time Frame: Through study completion (after 25 sport activities), an average of 6 weeks

Study Sites (1)

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