Effects of Acupuncture at ST36 and PC6 on Blood Pressure and Endothelial
Trial Snapshot
- Phase
- Phase 3
- Enrollment
- 32
- Locations
- 1
- Primary Endpoint
- To assess effects of acupuncture on endothelial function with FMD variation after 8 weeks treatments.
Study Overview
Brief Summary
This is randomised, controlled study about effects of acupuncture on blood pressure and endothelial dysfunction in stage I hypertension patient without medication. Subject will receive 8 weeks of either acupuncture or sham acupuncture, measuring FMD and blood test before and after treatment.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients age 18-70 diagnosed stage I hypertension ( JNC-7) without taking hypertensive medication
Exclusion Criteria
- •Secondary hypertension
- •History of cardiovascular disease
- •Taking hypertensive medication
- •Taking hyperlipidemic medication
- •Pregnancy or feeding woman
- •Cannot follow indication or there is no agreement of patient and conservator
- •Investigator decide Inappropriate to trial
Arms & Interventions
traditional acupuncture
Procedure : ST 36 and PC 6 are selected, subject will undergo 20minute sessions twice a week for 8weeks. Disposable acupuncture needle(4cm sterilized stainless steel) will be inserted up to 1 cm depth
Intervention: acupuncture (Procedure)
sham acupuncture
Procedure : Beside 1cm of ST 36 and PC 6 are selected( not meridian point), subject will undergo 20 minute. Disposable acupuncture needle(4cm sterilized stainless steel) will be inserted under 1 cm slightly.
Intervention: acupuncture (Procedure)
Outcomes
Primary Outcomes
To assess effects of acupuncture on endothelial function with FMD variation after 8 weeks treatments.
Time Frame: 8 weeks
Secondary Outcomes
- To examine the effects of acupuncture on blood pressure, lipid , hsCRP level variation with ABPM after 8 weeks treatments.(8 weeks)