Determining the correlation between echocardiographic blood flow velocity changes and breath holding maneuver to evaluate whether a hypotensive patient on ventilator support will be benefitted by further intravenous fluid therapy
Not Applicable
- Conditions
- Health Condition 1: I00-I99- Diseases of the circulatory system
- Registration Number
- CTRI/2019/12/022450
- Lead Sponsor
- ALL INDIA INSTITUTE OF MEDICAL SCIENCES NEW DELHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Mechanically ventilated patients of age 18 years and more admitted in the ICU.
2.Patients with Acute circulatory failure â?? presence of any one of the following.
-Systolic blood pressure <90 mm Hg or MAP < 65 mmHg
-Need of vasopressors to maintain systolic blood pressure > 90 mmHg.
-Urine output < 0.5ml/kg/hour for 2 hours
-Heart rate > 100 /min
Exclusion Criteria
Patients not in sinus rhythm
Patients with low tidal volumes (less than 6 ml/kg)
Patients with known cardiac valvular dysfunction
Right heart failure
Patients with very high respiratory rate (HR/RR <3.6)
Morbid obesity-BMI >=35 kg/m2
Poor echocardiographic window
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the correlation between pulmonary arterial velocity time integral variation, aortic velocity time integral variation and inspiratory pause maneuver to predict fluid responsiveness in mechanically ventilated patients with acute circulatory failure.Timepoint: 1 day
- Secondary Outcome Measures
Name Time Method To determine sensitivity, specificity, positive predictive value and negative predictive value of pulmonary arterial velocity time integral variation, aortic velocity time integral variation and inspiratory pause maneuver to predict fluid responsiveness in mechanically ventilated patients with acute circulatory failure.Timepoint: 1 day