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Clinical Trials/NCT02657421
NCT02657421
Terminated
N/A

A Multi-Center, Prospective, Observational Study to Assess Outcomes for Patients Treated for Lumbar Spinal Conditions Using an OLIF25™ and/or OLIF51™Approach

Medtronic Spinal and Biologics12 sites in 7 countries168 target enrollmentNovember 2015

Overview

Phase
N/A
Intervention
Not specified
Conditions
Degenerative Disc Disease
Sponsor
Medtronic Spinal and Biologics
Enrollment
168
Locations
12
Primary Endpoint
Back and Leg Pain Measured by Visual Analogue Scales (VAS)
Status
Terminated
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this single-arm observational study is to observe and document clinical outcomes of the OLIF25™ and OLIF51™ procedures in patients diagnosed with degenerative disc disease or degenerative scoliosis, and report the rate of adverse events of interest through the 24 months follow-up visit.

Registry
clinicaltrials.gov
Start Date
November 2015
End Date
May 3, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Medtronic Spinal and Biologics
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient is 18 years of age or older.
  • Patient agrees to participate in the study and is able to sign the informed consent/data release form.
  • Patient is undergoing surgery from L2-L5 for OLIF25™ and/or from L5-S1 for OLIF51™ for degenerative disc disease or degenerative scoliosis.

Exclusion Criteria

  • Illiterate or vulnerable patients (e.g. minors, participants incapable of judgment).

Outcomes

Primary Outcomes

Back and Leg Pain Measured by Visual Analogue Scales (VAS)

Time Frame: 24 months

Oswestry Disability Index (ODI)

Time Frame: 24 months

European Quality of Life-5 Dimensions (EQ-5D) self-report questionnaire

Time Frame: 24 months

Neurological deficits assessed by neurological status

Time Frame: 24 months

Neurological status is based on seven components of measurements: Motor function; Sensory function; Deep Tendon reflexes; Sympathetic Exam; Claudication; Urinary bladder retention/Bowel retention; and Sexual Dysfunction.

Rate of adverse events

Time Frame: 24 months

Study Sites (12)

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