Preoperative Nutritional Support in Esophagectomy or Pancreaticoduodenectomy
Not Applicable
Completed
- Conditions
- EsophagectomyPancreaticoduodenectomy
- Registration Number
- NCT00585624
- Lead Sponsor
- University of Wisconsin, Madison
- Brief Summary
We are proposing to evaluate the benefit of preoperative nutritional support with Impact Advanced Recovery in the most vulnerable group of elective gastrointestinal surgery patients who may experience a complication, esophagus and pancreas resections, and hypothesize that oral supplementation with 3 servings (0.75 L) Impact Advanced Recovery will reduce postoperative stay by 10-20% and reduce the incidence of major complications by 25%.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 344
Inclusion Criteria
- Male or female age 18 years or older of any race-ethnicity who will undergo an elective esophagectomy or pancreaticoduodenectomy.
- Surgery will be scheduled 5-7 days after consent date -
Exclusion Criteria
- Surgery is urgent or emergent and/or patient would be unable to consume nutritional supplement for 5-7 days
- Patient is currently receiving enteral (tube) or parenteral (IV) nutritional support
- Patients with known pre-existing renal failure requiring a low protein diet
- Patient is unable to drink 3 servings/day of a liquid supplement -
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Postoperative stay in days Postoperative stay in hospital & 30 days
- Secondary Outcome Measures
Name Time Method Incidence of major complications Postoperative stay in hospital & 30 days
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the efficacy of Impact Advanced Recovery in esophagectomy and pancreaticoduodenectomy patients?
How does preoperative Impact Advanced Recovery compare to standard nutritional support in reducing postoperative complications and hospital stay?
Are there specific biomarkers that predict response to preoperative nutritional supplementation with Impact Advanced Recovery in gastrointestinal surgery?
What are the potential adverse events associated with Impact Advanced Recovery and how are they managed in preoperative care?
What combination therapies or alternative nutritional supplements are being explored alongside preoperative interventions for esophagectomy and pancreaticoduodenectomy outcomes?
Trial Locations
- Locations (1)
University of Wisconsin Hospital & Clinics
🇺🇸Madison, Wisconsin, United States
University of Wisconsin Hospital & Clinics🇺🇸Madison, Wisconsin, United States