Extending spinal anesthesia: dexmedetomidine plus fentanyl

Not Applicable

Recruiting

• Conditions: Surgery; lengthy lower limb surgeries; Anaesthesia

• Registration Number: PACTR201703002122189
• Lead Sponsor: Faculty of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-22
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

¿Patients scheduled for major lower limb orthopedic procedures exceeding 4 hours as bilateral both lower limbs procedures or two procedures in one lower limb with possible bone grafting.
¿ASA I-III.
¿Both sexes.

Exclusion Criteria

¿Patient refusal.
¿Hypersensitivity to used anesthetics,
¿General contraindications to spinal anesthesia,
¿Cardiac, hepatic, renal or respiratory failure.
¿Difficult communication.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
¿The time till first pain sensation.;¿The time till Bromage score 0 (full leg movement)

Secondary Outcome Measures

Name	Time	Method
¿The required doses of intraoperative iv midazolam, fentanyl and propofol. ;¿The rate of conversion to general anesthesia.;Intraoperative hemodynamics (MBP, HR) ;postoperative hemodynamics (MBP, HR) ;Maximum and minimum MBP and HR ;Required doses of atropine and ephedrine ;Incidence of using oxygen face mask (SaO2 less than 90%).;estimated blood loss ;The number of packed RBCs transfusion units;The volume of fluids administration ;Incidence of shivering, itching, nausea & vomiting;Incidence of sedation, shivering, itching, nausea & vomiting;The total morphine requirements ;Visual analogue scale (VAS);Duration of hospital stay;Patient satisfaction in a score (0 - 10)