Herpes Zoster: Risk Factors, Complications and Special Situations- a Retrospective Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 355
- 试验地点
- 1
- 主要终点
- Evaluation of patients' history
研究概览
简要总结
This retrospective analysis is to investigate patients' history and clinical presentation in Herpes Zoster (HZ), Zoster-related complications, post-Zoster neuralgia and Herpes Zoster management in order to improve the management of HZ patients, to refine HZ-vaccination strategies and elucidate cost factors of HZ in in the setting of a university hospital in Switzerland generally and in a dermatology department specifically.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Reports of patients with HZ at University Hospital Basel between 2004-2018
排除标准
- •rejection to use patient data
结局指标
主要结局
Evaluation of patients' history
时间窗: single time point assessment at baseline
Free text evaluation of patients' history (age, sex, comorbidities, immunosuppression, obesity, human immune deficiency Virus (HIV), profession, current medication, vaccinations, seasonal occurence of HZ, history of Varicella Zoster virus (VZV) infection
Description of the clinical presentation of HZ
时间窗: single time point assessment at baseline
Free text description of the clinical presentation of HZ (localisation, dermatomes affected), Zoster-related acute pain
Evaluation of the herpes zoster management
时间窗: single time point assessment at baseline
Free text evaluation of the herpes zoster management (local (antiviral) treatment, systemic antiviral and other treatments, number of revisits, average treatment-related costs, hospitalisations (rate, duration)
Assessment of post-zoster neuralgia
时间窗: single time point assessment at baseline
Free text assessment of post-zoster neuralgia (annual incidence, treatment options used)
Evaluation of zoster and pregnancy
时间窗: single time point assessment at baseline
Free text evaluation of zoster and pregnancy (incidence, time of pregnancy, pregnancy outcomes and complications)
Evaluation of zoster-related complications
时间窗: single time point assessment at baseline
Free text evaluation of zoster-related complications (ophthalmic zoster, generalised HZ, Ramsay-Hunt syndrome, zoster meningoencephalitis)
次要结局
未报告次要终点