The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance

• Conditions: Metabolic Syndrome X; Cachexia; Insulin Resistance

• Registration Number: NCT00172614
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases. Cytokines secreted by adipose tissue and inflammatory cells play important roles in the pathological conditions. Several novel cytokines were disclosed recently, but their functions have not been well known. Further investigation of these cytokines, resulting in insulin resistance and energy homeostasis, is very important to elucidate the mechanisms and develop new therapeutic strategies.

Detailed Description

We are studying patients with body weight change, increased or decreased. Healthy people are the control group. We are recording body weight, body height, and physical exam results. In addition, we are drawing peripheral blood for further biochemical and cytokine assays.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2004-12
• Study Start: 2004-12
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Study First Posted: 2005-09-15
• Last Update Submitted: 2006-03-28
• Last Update Posted: 2006-03-29

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Insulin resistance condition

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan