The Relationship Between Previously Unknown Glucose Metabolism Disorders and Coronary Artery Disease in Patients Suffering From Coronary Artery Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diabetes Mellitus
- Sponsor
- Gulhane School of Medicine
- Enrollment
- 230
- Locations
- 1
- Primary Endpoint
- Frequency of unknown glucose metabolism disorders in patients with coronary artery disease
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
This study aimed to examine the prevalence of glucose metabolism disorders (GMD)in the patients with coronary artery disease and the relationship between different GMDs and coronary artery disease (CAD).
Detailed Description
Context: There are more than 220 million people diagnosed with diabetes mellitus (DM) in the world. DM is a serious risk factor for coronary artery disease (CAD). This study aimed to examine the prevalence of glucose metabolism disorders (GMD) in te patients with coronary artery disease and the relationship between different GMDs and CAD. Settings: 230 patients with coronary artery disease and without any known GMDs were included the study. Coronary angiography was used to diagnose CAD. Patients were administered the 75 g Oral Glucose Tolerance Test (OGTT).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with coronary artery disease and who had no glucose metabolism disorders were included to study.
Exclusion Criteria
- •Patients who had previous GMDs, malignancies, chronic liver and kidney diseases, rheumatologic disorders, and a BMI higher than 35 kg/m2 were excluded from the study.
Outcomes
Primary Outcomes
Frequency of unknown glucose metabolism disorders in patients with coronary artery disease
Time Frame: 1 year
Results: While GMDs were detected in 58.26% (n=134 patients) of CAD patients, 41.74% of them (n=96 patients) were found to have normal glucose metabolism.
Secondary Outcomes
- Fasting and 120 minute glucose levels have relation with vessels' stenosis.(1 year)