NCT00698282已完成1 期
A Randomised, Placebo-Controlled, Double-Blind, Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Doses of AZD1981 in Healthy Male Japanese and Caucasian Subjects
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Adverse events
研究概览
简要总结
The purpose of this study is to study safety, tolerability and pharmacokinetics of AZD1981 in healthy Japanese subjects
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy Japanese and Caucasian males
排除标准
- •Other clinically relevant disease or disorders
研究组 & 干预措施
1
Experimental
干预措施: AZD1981 (Drug)
2
Experimental
干预措施: AZD1981 (Drug)
3
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
Adverse events
时间窗: All the time
Plasma drug concentration
时间窗: Every hour
次要结局
- Clinical chemistry(day 1 and 9)
研究者
研究点 (1)
Loading locations...
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