NCT02957279Unknown不适用
A Cohort Study to Investigate the Impacts of Peripheral Blood Dendritic Cells-Derived Exosomes at Early Phase on the Prognosis in Human Sepsis
Jinling Hospital, China1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2016年11月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Amount of dendritic cell-derived exosomes
研究概览
简要总结
The amount of peripheral blood exosomes has been confirmed to change in the endotoxin-induced infection. The primary objectives of this study are to compare the changes of peripheral blood dendritic cell-derived exosomes in the patients with sepsis and the healthy controls.
详细描述
This is a prospective, single-centered, clinical cohort study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients were selected with the diagnostic standard "Sepsis 3.0".
- •Healthy volunteers do not have serious illness.
排除标准
- •Patients or volunteers do not agree to provide written informed consent and / or can not be legally authorized to provide informed consent.
- •Patients give up treatments.
- •Patients or volunteers withdrew from the study.
研究组 & 干预措施
Sepsis group
The patients were admitted to the Jinling Hospital, who met the diagnosis of sepsis(Sepsis 3.0).
干预措施: Antibiotics (Drug)
结局指标
主要结局
Amount of dendritic cell-derived exosomes
时间窗: The first 4 hour after admission
次要结局
- Compositions of microRNA in the dendritic cell-derived exosomes(The first 4 hour after admission)
研究者
Jianan Ren
President of department of surgery, Jinling Hospital
Jinling Hospital, China
研究点 (1)
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