â??Comparing topical Clindamycin - Adapalene with oral doxycycline 100mg versus topical Benzoyl peroxide - Adapalene with oral doxycycline 100mg in moderate to severe facial acne vulgaris
Not Applicable
- Conditions
- Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
- Registration Number
- CTRI/2023/02/050053
- Lead Sponsor
- tamil selvi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Subjects of either gender.
2. Subjects of 12 to 30 years of age with moderate to severe facial acne vulgaris having >= 19 and <=38 score based on global acne grading system.
Exclusion Criteria
Patients already on anti-acne medication(topical or oral) in last one month.
2. Patients having nodulocystic lesions, acne conglobata, acne fulminans, secondary acne.
3. Patients unwilling to give written informed consent.
4. Patients with known hypersensitivity to benzoyl peroxide, clindamycin or adapalene and doxycycline.
5. Pregnant or lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Efficacy and safety assessed from baseline at 4 and 8 weeks <br/ ><br>cost effectiveness assessed at 8 weeksTimepoint: From baseline at the end of 4 and 8 weeks, <br/ ><br>
- Secondary Outcome Measures
Name Time Method Adverse event <br/ ><br>cost effectiveness evaluatedTimepoint: 2,4 AND 8 WEEKS