Lifestyle Changes in Fatty Liver; Additive Effect of Honey Intake

Not Applicable

Recruiting

• Conditions: Fatty Liver, Nonalcoholic
• Interventions: Behavioral: honey intake and lifestyle changes; Behavioral: lifestyle changes

• Registration Number: NCT06596109
• Lead Sponsor: Cairo University

Brief Summary

honey is a natural functional food used in control cardiovascular risk factors but its effect on fatty liver is not investigated

Detailed Description

Forty fatty liver (non-alcoholic from) patients with obesity are included to be divided into group 1 who will contain 20 patients who will receive honey intake (orally, as a daily total dose of 2 g/kg, this dose will be divided to three equal subdoses, every dose will be administered before meal), low calorie diet, and treadmill walking (40 minutes per session, three times per week) for 12 weeks. Group 2 who will contain 20 patients who will receive low calorie diet, and treadmill walking (40 minutes per session, three times per week) for 12 weeks.

Study Timeline

• Status Verified: 2024-09
• Study Start: 2024-09-10
• Study First Submitted: 2024-09-11
• Study First Submitted QC: 2024-09-11
• Last Update Submitted: 2024-09-11
• Study First Posted: 2024-09-19
• Last Update Posted: 2024-09-19
• Primary Completion: 2025-01-30
• Study Completion: 2025-02-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• fatty liver (non alcoholic form)
• both sexes included
• obese subjects (class I)

Exclusion Criteria

• cardiac insult
• respiratory insult
• renal insult
• lower limb insult

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
honey intake and lifestyle changes	honey intake and lifestyle changes	Twenty fatty liver (non-alcoholic from) patients with obesity are included as 20 patients who will receive honey intake (orally, as a daily total dose of 2 g/kg, this dose will be divided to three equal subdoses, every dose will be administered before meal), low calorie diet, and treadmill walking (40 minutes per session, three times per week) for 12 weeks.
lifestyle changes	lifestyle changes	Twenty fatty liver (non-alcoholic from) patients with obesity are included as 20 patients who will receive low calorie diet, and treadmill walking (40 minutes per session, three times per week) for 12 weeks.

Primary Outcome Measures

Name	Time	Method
High density lipoprotein	it will be assessed after 12 weeks	it will be measured in serum

Secondary Outcome Measures

Name	Time	Method
triglycerides	it will be assessed after 12 weeks	it will be measured in serum
cholesterol	it will be assessed after 12 weeks	it will be measured in serum
low density lipoprotein	it will be assessed after 12 weeks	it will be measured in serum
alanine transamianse	it will be assessed after 12 weeks	it will be measured in serum
aspartate transamianse	it will be assessed after 12 weeks	it will be measured in serum
fasting blood glucose	it will be measured after 12 weeks	it will be measured in serum
body mass index	it will be measured after 12 weeks	it will be measured on empty stomach
waist circumference	it will be measured after 12 weeks	it will be measured on empty stomach

Trial Locations

Locations (1)

faculty of physical therapy Cairo university; 🇪🇬 Dokki, Giza, Egypt