NL-OMON33167
Completed
Not Applicable
A double-blind functional MR study to investigate the stability of the signal at baseline and following the administration of cognitive tests in placebo condition and after oral administration of a benzodiazepine in young healthy male subjects - Reproducibility of cognitive fMRI tests after placebo and benzodiazepine
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- neurosciences
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 20
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy, right\-handed male individuals between 18\-25 year \-o.
Exclusion Criteria
- •Female sex.
- •Previous participation in a study with MRI.
- •Clinically significant history of drug allergies (benzodiazepines).
- •Recent history (within previous 6 months) of alcohol or drug abuse.
- •History of or current significant medical illness including cardiac arrhythmias or other cardiac disease, hematological disease, bronchospastic respiratory disease, dyspnea, diabetes mellitus, renal or hepatic insufficiency, thyroid disease, infection, or any other illness that the investigator considers clinically significant.
- •History of or current psychiatric or neurological illness.
- •Smoking cigarettes (or equivalent) or the use of nicotine based products, within 3 months prior to study drug administration
- •Positive urine screen for drugs of abuse at screening or admission.
- •Use of any prescription or over\-the\-counter psychotropic medication (including herbal medications) within 2 weeks of dosing with the study drug.
- •Visual disorder that cannot be corrected through the use of corrective lenses
Outcomes
Primary Outcomes
Not specified
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