NCT06775574已完成不适用
Prognostic Significance of the Lung Immune Prognostic Index (LIPI) in Postoperative Clear Cell Renal Cell Carcinoma: a Multicenter Retrospective Cohort Study
Wuhan Union Hospital, China1 个研究点 分布在 1 个国家目标入组 704 人开始时间: 2014年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 704
- 试验地点
- 1
- 主要终点
- overall survival (OS)
研究概览
简要总结
This retrospective study included 704 patients with ccRCC who underwent radical or partial nephrectomy. Patients were stratified into the LIPI good group and the intermediate/poor (int./poor) group based on dNLR (≥ 3) and LDH (≥ 245 U/L) levels. Propensity score matching (PSM) was used to adjust for baseline differences and minimize selection bias. Kaplan-Meier survival curves and Cox regression models were employed to evaluate the impact of LIPI and other clinical factors on recurrence-free survival (RFS) and overall survival (OS).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pathologically diagnosed with ccRCC;
- •Underwent radical or partial nephrectomy.
排除标准
- •presence of concurrent malignancies;
- •missing data or failure to follow-up
结局指标
主要结局
overall survival (OS)
时间窗: 5 years
recurrence-free survival (RFS)
时间窗: 5 years
次要结局
未报告次要终点
研究者
研究点 (1)
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