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临床试验/NCT03058133
NCT03058133已完成不适用

Neural Correlates of Multimodal Face/Voice Processing in a Gender Task.

Hospices Civils de Lyon2 个研究点 分布在 1 个国家目标入组 38 人开始时间: 2016年5月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
38
试验地点
2
主要终点
Identify neural correlates (fMRI) of face / voice interaction in a gender classification task

研究概览

简要总结

Bayesian models of perception represent a promising approach to describe information processing by the brain. Predictive coding hypothesizes a process in which top-down expectations are continuously compared across multiple hierarchical levels with bottom-up sensory inputs and the differences or error signals are propagated in a bottom-up direction. The investigators hypothesize that strong expectations, are best investigated in expert processes such as face and voice recognition in humans. Individuals in complex social systems need to extract socially relevant information in a fast and efficient manner; hence, the majority of humans constitute face, voice and gender experts. Nevertheless, linking such combined abilities to brain activity with regards to the predictive coding hypothesis has not been attempted.Our results suggest asymmetric contributions of visual and auditory signals to the gender classification task. This sensitive psychophysical procedure is implemented in a decoding approach using fMRI and multi-voxel pattern analysis (MVPA). The investigators plan to test whether cortical areas implicated in processing auditory and visual gender signals show similar asymmetries.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Healthy men and women, right-handed
  • •No neurological antecedent
  • •Signed informed consent

排除标准

  • •Pregnant women
  • •Volunteers with MRI contraindications: persons using a pacemaker or insulin pump, persons with a metallic prosthesis or an intracerebral clip, as well as claustrophobic subjects, neurosensory stimulator or implantable defibrillator, cochlear implants, body Foreign ferromagnetic ocular or cerebral close to nerve structures, agitation of the subject (non-cooperating or agitated subjects), ventriculoperitoneal neurosurgical bypass valves, dental apparatus.
  • •Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights or liberty, as well as persons of legal age protected by law.
  • •Participants refusing to be informed of the results of the medical examination (inclusion).
  • •Participants refusing to be informed of the possible detection of an anomaly.

研究组 & 干预措施

fMRI study

Other

干预措施: fMRI study (Other)

结局指标

主要结局

Identify neural correlates (fMRI) of face / voice interaction in a gender classification task

时间窗: Maximum 90 days between inclusion of the subject and the 1st fMRI session (1h1 / 2). Then maximum 90 days before the 2nd session (1h1 / 2).

Classical functional analyses (GLM) and advanced statistical analyses of brain activations (BrainVoyager and Matlab softwares).

Identify neural correlates (fMRI) of face / voice respective contribution in a gender classification task

时间窗: Maximum 90 days between inclusion of the subject and the 1st fMRI session (1h1 / 2). Then maximum 90 days before the 2nd session (1h1 / 2).

Classical functional analyses (GLM) and advanced statistical analyses of brain activations

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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Gender in Face-Voice Integration | 临床试验