Efficacy of pregnenolon in treatment of irritability inteeanagers with autism

Phase 3

Recruiting

• Conditions: F84.0; Autistic disorder.; Autistic disorder

• Registration Number: IRCT20090117001556N112
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 May 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

DSM-5 clinical diagnosis of autistic disorder
Teenagers between the ages of 11and 17 years old
Presence of behavioral problems such as aggression, overactivity or repetitive behaviors (indication of treatment with risperidone)

Exclusion Criteria

Presence of any active medical problem
Other psychiatric diagnosis except for mild to moderate Intellectual disability
Receiving any antipsychotic medications during past monthprior to the trial
Severe hepatic disease
History of allergy to risperidone and intolerance of it
History of seizure requiring change of antiepileptic dose during the last month
Seizure during the last 6 months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of autism. Timepoint: Baseline and weeks 5, and 10. Method of measurement: By Aberrant Behavior Checklist-Community( ABC-C).