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临床试验/PACTR202004634203807
PACTR202004634203807已完成未知

Pre-operative Vaginal Cleaning with Chlorhexidine Solution in Preventing Post-Caesarean Section Infections at the Federal Teaching Hospital, Abakaliki: A Randomized Controlled Trial

ogah okechukwu c0 个研究点目标入组 168 人开始时间: 2020年2月8日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
168

研究概览

简要总结

The study showed that the use of 1% chlorhexidine in cleaning the vaginal before emergency caesarean section significantly reduced infectious morbidities like endometritis, decreased hospital stay. It had no effect on surgical site infection. Endo-cervical colonization by micro-organisms was significantly higher in the control 11(14%) in study group versus 41(51)% in control group, (RR) = 0.37,95% CI {0.21 – 0.64}, P 0.0001. Fowl smelling vaginal discharge was 2(2.6%) in study group versus 18(22.5%), (RR) = 9.5, 95% CI {1.30 – 64.55}, P 0.0002. Abdominal tenderness was also higher in the control group 3(3.8%) for study versus 15(30%) for control, (RR) = 2.87, 95% CI {1.00 – 8.21}, P 0.0133. Fever was also lower in the study group but was not statistically significant P value 0.286.

研究设计

研究类型
Interventional

入排标准

年龄范围
19 Year(s) 至 44 Year(s)(—)
性别
Female

入选标准

  • Consented pregnant women undergoing emergency caesarean section at FETHA.
  • All unbooked patients undergoing caesarean section after informed consent
  • Patients who have been in labour for four hours or more after hospital admission.

排除标准

  • Women with features of clinical chorioamnionitis
  • Women with fever (temperature = 38 degree C)
  • Fetal distress as an indication for CS
  • Placenta previa diagnosed on ultrasound
  • Anaemia (pack cell volume less than 21%)
  • Uncontrolled Gestational diabetes mellitus

研究者

发起方
ogah okechukwu c

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