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Clinical Trials/NCT01848587
NCT01848587
Completed
Phase 3

Trial of Acupuncture Pelvic and Low Back Pain in Pregnancy (TAPPP)

Assistance Publique - Hôpitaux de Paris1 site in 1 country200 target enrollmentSeptember 2012

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Disorder of Pregnancy
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment
200
Locations
1
Primary Endpoint
Number and % of days during pregnancy with maximum pain ≤ 4/10.
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Pelvic girdle and low back pain are common in pregnancy, and cause severe impairment in 10% of women. Our hypothesis is that offering acupuncture in addition to standard care would reduce pain and impairment throughout pregnancy. 300 pregnant women from 5 maternity units will be randomized over a 3 year period to receive standard care or standard care plus acupuncture. Main outcome will be the number of days during pregnancy with maximum pain ≤ 4/10. Secondary outcomes will compare groups for an impairment score and for direct and indirect costs.

Detailed Description

Background. Pelvic and low back pain (PLBP) affects 30% of pregnant women for weeks or months, causing severe impairment in 10% of women. Standard treatment, based on pain killers, postural recommendations, exercises, is of limited value. Previous trials showed that adding acupuncture to standard treatment reduces pain and impairment in the short run. Hypothesis Providing acupuncture to pregnant women with PLBP could reduce pain and impairment throughout pregnancy, thus reducing other direct and indirect cots related to PLBP. Primary Outcome. Number and % of days during pregnancy with maximum pain ≤ 4/10. Secondary Outcomes. Pain scale 4 weeks after inclusion, mean Oswestry disability score between inclusion and delivery, direct costs related to pregnancy care and pain management, indirect costs related to impairment throughout pregnancy and the immediate postpartum. Method. Multicenter randomized trial with parallel groups. Intervention: 5 acupuncture sessions over 4 weeks, plus standard treatment. Controls: standard treatment. Analysis per pregnancy Follow up: logbook kept by he patient plus analysis of obstetrical records. Number of patients: 300 Inclusion criteria: singleton uncomplicated 16-34 weeks pregnancy, with PLBP \> 4/10 Exclusion criteria Obstetrical complication other than PLBP, contra indication to acupuncture, sciatica, maternal age \< 18, no health insurance. Duration. Overall duration: 3 years and 6 months, inclusions over 3 years. Duration of inclusion per patient: 2-26 weeks Number of participating centers 5

Registry
clinicaltrials.gov
Start Date
September 2012
End Date
March 2015
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • singleton uncomplicated 16-34 weeks pregnancy, with PLBP \> 4/10

Exclusion Criteria

  • Obstetrical complication other than PLBP,
  • contra indication to acupuncture,
  • maternal age \< 18
  • no health insurance.

Outcomes

Primary Outcomes

Number and % of days during pregnancy with maximum pain ≤ 4/10.

Time Frame: at 4 weeks

daily recording on logbook (self assessment)

Secondary Outcomes

  • Mean Oswestry disability score(during pregnancy)
  • Number and % of days with maximum pain ≤ 4/10.(during pregnancy)
  • direct and indirect costs(during pregnancy)

Study Sites (1)

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